應(yīng)用范圍：
Arthro-BST?在軟骨修復(fù)研究中有著重要的應(yīng)用。
l 有助于理解軟骨**（如軟骨退行）的發(fā)病原因
l 開發(fā)新的**產(chǎn)品和軟骨修復(fù)技術(shù)
l 構(gòu)建穩(wěn)定的關(guān)節(jié)炎動物模型
應(yīng)用文獻(xiàn)：
Scientific Publications & Material Related to Arthro-BST?
2016
S. Sim, C. Becher, M. Garon, E. Quenneville, C. Hurschler and M.D. Buschmann. Comparison Between In Vitro and Simulated Arthroscopy Electromechanical Measurements of Human Articular Surfaces Using the Arthro-BST. International Cartilage Repair Society, Sorrento, Italy, Sept 2016. Poster #132
Sim S, Chevrier A, Garon M, Quenneville E, Lavigne P, Yaroshinsky A, Hoemann CD, Buschmann MD. Electromechanical probe and automated indentation maps are sensitive techniques in assessing early degenerated human articular cartilage. J Orthop Res. 2016 Jun 9. doi: 10.1002/jor.23330.Abstract
Jan C. Schagemann, Nicola Rudert, Michelle E. Taylor, Sotcheadt Sim, Eric Quenneville, Martin Garon, Mathias Klinger, Michael D. Buschmann, and Hagen Mittelstaedt (2016) Bilayer Implants: Electromechanical Assessment of Regenerated Articular Cartilage in a Sheep Model. Cartilage, 1947603515623992, first published on January 22, 2016. Abstract
2015
Mickevicius, T., Pockevicius, A., Kucinskas, A., Gudas, R., Maciulaitis, J., Noreikaite, A., and Usas, A. (2015). Impact of storage conditions on electromechanical, histological and histochemical properties of osteochondral allografts. BMC musculoskeletal disorders, 16(1), 314. Abstract, Article
Hadjab I., Sim S., E. Quenneville, M. Garon and M.D. Buschmann. (2015) Assessment of Human Articular Cartilage Issued from Asymptomatic and TKR Donors. Biomedical Engineering Society (BMES) Annual Meeting, Tampa, FL, USA. Presentation OP-Thurs-3-8. Thursday, October 8, 2015, 4:30 PM - 6:00 PM, Room 14.
Christoph Becher, Marcel Ricklefs, Elmar Willbold, Christof Hurschler, and Reza Abedian (2015) Electromechanical Assessment of Human Knee Articular Cartilage with Compression-Induced Streaming Potentials, Cartilage, 1947603515599191, first published on August 13, 2015. Abstract
S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann. Correlation of Non-destructive Electromechanical Probe (Arthro-BST) Assessment with Histological Scores and Mechanical Properties in Human Tibial Plateau. Podium presentation 23.2.8 Osteoarthritis - Basic Science 2 and Biomechanics, Monday, May 11, 10:00 - 11:30, Chicago 9. Abstract / Presentation
S. Sim, I. Hadjab, M. Garon, E. Quenneville, M.B. Hurtig, M.D. Buschmann, and C.D. Hoemann. Evaluation of Entire Ovine Cartilage Repair Articular Surfaces: Mechanical and Electromechanical Assessment. Poster Presentation (P87). Abstract / Poster / ePoster
J.C. Schagemann, N. Rudert, S. Sim, E. Quenneville, M. Garon, M.E. Casper, M. Klinger, M.D. Buschmann, and H. Mittelstaedt. Correlation of Traditional and Novel Outcome Measures for the Assessment of Regenerated Osteochondral Tissue in a Sheep Model. Poster Presentation (P83). Abstract / Poster
S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann. Correlation of Non-destructive Electromechanical Probe (Arthro-BST) Assessment with Histological Scores and Mechanical Properties in Human Tibial Plateau. OARSI 2015 World Congress on Osteoarthritis, April 30-3, 2015, Seattle, USA. Poster 368
S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann. Correlation of Non-destructive Electromechanical Probe (Arthro-BST) Assessment with Histological Scores and Mechanical Properties in Human Tibial Plateau. 61st Annual Meeting of the ORS, March 28-30, 2015, Las Vegas, USA.Poster 1228
2014
S. Sim, A. Chevrier, M. Garon, E. Quenneville, A. Yaroshinsky, C.D. Hoemann and M.D. Buschmann. Non-destructive Electromechanical Assessment (Arthro-BST) of Human Articular Cartilage Correlates with Histological Scores and Biomechanical Properties. Osteoarthritis and Cartilage, 2014 Aug 25. pii: S1063-4584(14)01221-7. Abstract
A. Changoor, W. Brett, M.A. Hoba, M. Garon, E. Quenneville, K. Gordon, P. Savard, M.D. Buschmann, M.B. Hurtig and D.R. Trout. Electroarthrography, a non-invasive streaming potential-based method, measures cartilage quality in live horses. Osteoarthritis and Cartilage, Vol. 22, Supplement 1, 138, World Congress on Osteoarthritis, April 2014, Paris, France. Poster
S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann. Correlation of Non-destructive Electromechanical Probe (Arthro-BST) Assessment with Histological Scores, Biochemical Composition and Mechanical Properties in Human Knee Joints. Transactions of the 60th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 0439. Poster
A. Changoor, M.A. Hoba, M. Garon, E. Quenneville, K. Gordon, P. Savard, M.D. Buschmann, M.B. Hurtig. Non-invasive Electroarthrography Correlates to Direct Measurements of Cartilage Streaming Potentials in Weight Bearing Regions of Equine Metacarpophalangeal (Fetlock) Joints. Transactions of the 60th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 1123. Poster
2013
S. Sim, A. Chevrier, E. Quenneville, M. Garon, and M.D. Buschmann. Correlation of Non-destructive Electromechanical Probe (Arthro-BST) Assessment with Histological Scores and Mechanical Properties in Human Knee Joints. Transactions International Cartilage Repair Society, P26, September 2013, Izmir, Turkey. Poster
Sim S., Picard G., Quenneville E., Garon M. and Buschmann M.D. (2013) The Spatial Pattern of Articular Cartilage Electromechanical Properties in the Stifle Joint is Similar in Three Different Species. Ecole Polytechnique of Montreal, Chemical Engineering Research Day, March 14th 2013. Presentation
Abedian R., Willbold E., Becher C. and Hurschler C. (2013) In vitro electro-mechanical characterization of human knee articular cartilage of different degeneration levels: A comparison with ICRS and Mankin scores. Journal of Biomechanics, accepted 5 February 2013, published online 11 March 2013.Abstract
Sim S., Picard G., Quenneville E., Garon M. and Buschmann M.D. (2013) The Spatial Pattern of Articular Cartilage Electromechanical Properties in the Stifle Joint is Similar in Three Different Species. Transactions of the 59th Annual Meeting of the Orthopaedic Research Society, San Antonio, TX, USA, 1975. Poster
Sim S., Picard G., Quenneville E., Garon M. and Buschmann M.D. (2013) Age-dependence of the Pattern of Cartilage Electromechanical Properties in the Ovine Stifle Joint Transactions of the 59th Annual Meeting of the Orthopaedic Research Society, San Antonio, TX, USA, 1976. Poster
Changoor A., Hoba M.A., Quenneville E., Garon M., Gordon K., Buschmann M.D., Savard P., Hurtig M.B. (2013) Electroarthrography Provides a Non-invasive Streaming Potential-Based Method for Detecting Cartilage Degeneration in an Equine Model Transactions of the 59th Annual Meeting of the Orthopaedic Research Society, San Antonio, TX, USA, 1974. Poster
2012
Sim S., Picard G., Quenneville E., Garon M. and Buschmann M.D. (2012) The Spatial Pattern of Articular Cartilage Electromechanical Properties in the Stifle Joint is Similar in Three Different Species. Groupe de recherche en sciences et technologies biomédicales (GRSTB) Symposium - Biomechanics and biomaterials, October 10, 2012, école Polytechnique de Montreal, Montreal, Quebec, Canada. Poster
2011
Presentation by Prof. Dr. Dani?l Saris, MD, PhD of the Arthro-BST at the ICRS 4th Surgical Skills Course, in Rostock (Germany), August 25-27, 2011.Video 
Report following the ICRS Laboratory Skills Course in Translational Science in Montreal (Quebec, Canada), from May 31 to June 3, 2011. Report
Changoor, A., Coutu, J. P., Garon, M., Quenneville, E., Hurtig, M. B., Buschmann, M. D. (2011) Streaming Potential-Based Arthroscopic Device is Sensitive to Cartilage Changes Immediately Post-Impact in an Equine Cartilage Injury Model. J. Biomech. Eng. 2011 Jun. 133(6):061005. Abstract
Changoor, Adele (2011) Electromechanical And Polarization Microscopy Evaluation Of Cartilage Repair And Degeneration, Ecole Polytechnique of Montreal, Ph.D. thesis. Thesis
2010
Changoor A, Fereydoonzad L, Yaroshinsky A, Buschmann MD. (2010) Effects of refrigeration and freezing on the electromechanical and biomechanical properties of articular cartilage. J Biomech Eng. 2010 Jun;132(6):064502. Abstract
2009
Changoor A., Quenneville E., Garon M., Hurtig M.B., Buschmann, M.D., (2009) Streaming Potential-Based Arthroscopic Device Can Detect Changes Immediately Following Localized Impact in an Equine Impact Model of Osteoarthritis. Osteoarthritis and Cartilage, Vol. 17, Supplement 1, S53, World Congress on Osteoarthritis, September 2009, Montreal, Quebec, Canada. Poster
2008
Hurtig M.B., Quenneville E., Garon M., Buschmann M.D. Legare A. (2008) Evaluation of a Medical Device for Assessment of Cartilage Degeneration After Impact Injury. Transactions of the 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, USA, 33:723. Poster
Garon M., Buschmann M.D., (2008) Non-Homogeneous Electromechanical Properties of articular Cartilage Predict an Electrical Potential of Positive Polarity outside Cartilage. Transactions of the 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, USA, 33:629. Poster
2007
Changoor A., Quenneville E., Garon M., Cloutier L., Hurtig M.B., Buschmann, M.D., (2007) Streaming Potential-Based Arthroscopic Device Discerns Topographical Differences In Cartilage Covered And Uncovered By Meniscus In Ovine Stifle Joints. Transactions of the 53th Annual Meeting of the Orthopaedic Research Society, San Diego, CA, USA, 32:631. Poster
Garon, Martin (2007) Conception et validation d'une sonde arthroscopique pour l'évaluation des propriétés électromécaniques fonctionnelles du cartilage articulaire (Conception and Validation of an Arthroscopique Probe for Evaluation of Functional Electromechanical Properties of Articular Cartilage), Ecole Polytechnique of Montreal, Ph.D. thesis. Thesis (in French with Abstract in English)
Garon M., Legare A., Quenneville E., Sims T.J., Hollander A.P., Shive M.S., Restrepo A., Buschmann M.D., (2007) Arthroscopic Device Measuring Streaming Potentials Reliably indicates Functional Properties of Cartilage. Osteoarthritis and Cartilage, Vol. 15, Supplement C, 254, World Congress on Osteoarthritis, December 2007, Ft. Lauderdale, Florida, USA. Poster
Garon M., Legare A., Quenneville E., Sims T.J., Hollander A.P., Hurtig M.B., Shive M.S., Buschmann M.D., (2007) Cartilage Streaming Potentials Measured with an Arthroscopic Medical Device Correlate with Site-specific Biochemical and Biomechanical Properties of Equine Articular Cartilage. Transactions International Cartilage Repair Society, 22.6, September 2007, Warsaw, Poland. Slides
Garon M., Legare A., Quenneville E., Sims T.J., Hollander A.P., Shive M.S., Restrepo A., Buschmann M.D., (2007) Streaming Potentials Measured with an Arthroscopic Medical Device are Reliable Indicators of Biochemical and Biomechanical Properties of Human Articular Cartilage. Transactions International Cartilage Repair Society, 5.3, September 2007, Warsaw, Poland. Slides
Garon M., Cloutier L., Legare A., Quenneville E., Shive M.S., Buschmann M.D., (2007) Reliability and Correlation to Human Articular Cartilage Mechanical Properties of a Streaming Potential based Arthroscopic Instrument. Transactions of the 53th Annual Meeting of the Orthopaedic Research Society, San Diego, CA, USA, 32:629. Poster
Larouche, Antoine (2007) Détermination de l'épaisseur du cartilage articulaire par mesures de la conductivité électrique (Determination of Articular Cartilage Thickness by Electrical Conductivity Measurements), Ecole Polytechnique of Montreal, Master in Applied Science (M.A.Sc.) Thesis.
Master Thesis (in French with Abstract in English)
Quenneville E, Garon M, Légaré A, Shive M, and Buschmann MD (2007a). Mapping Articular Cartilage Function using a Streaming Potential-based Arthroscopic Device. Transactions of the Segal North American Osteoarthritis Workshop (Chicago, USA). Poster
Quenneville E, Buschmann MD (2007b). A novel approach to predict diagnostic electric potential in cartilage. Transactions of the Orthopedic Research Society. 32 630. Poster | Abstract
2006
Changoor A., Quenneville E., Garon M., Cloutier L., Légaré A., Hurtig M.B., Buschmann M.D. (2006). Streaming potential-based arthroscopic device discerns topographical differences in cartilage covered and uncovered by meniscus in ovine stifle joints. Transactions of the Canadian Arthritis Network (Winnipeg, Canada). Poster
Li LP, Herzog W., (2006). Arthroscopic evaluation of cartilage degeneration using indentation testing--influence of indenter geometry. Clin. Biomech. May;21(4):420-6. Epub 2006 Feb 2. Abstract
Quenneville, Eric (2006) Les distributions de potentiel électrique dans le cartilage articulaire (Electrical Potential Distributions in Articular Cartilage), Ecole Polytechnique of Montreal, Ph.D. thesis. Thesis (in French with Abstract in English)
2005
Li LP, Herzog W., (2005). Electromechanical response of articular cartilage in indentation--considerations on the determination of cartilage properties during arthroscopy. Comput. Methods Biomech. and Biomed. Engin. Apr;8(2):83-91. Abstract
Quenneville E, Garon M, Légaré A, Garon M, and Buschmann MD. (2005a) Arthro-BST: A Diagnostic Instrument for the Functional Evaluation of Articular Cartilage. AITS Innovation Research Contest, Montréal, Mars 2005 Slides
Quenneville E., and Buschmann M.D. (2005b), A transport model of convection of electrolyte through a charged membrane predicts generation of net charge at membrane interfaces. Journal of Membrane Science, 265 (1-2), 60-73, 2005. Abstract
2004
Buschmann, M. D., Légaré, A., Garon, M. and Savard, P. (2004). Characterization of the Contact Distribution between Two Arbitrary Surfaces using Electrode Arrays. Patent 1199983 (Germany).
Quenneville E., Garon M., Legare A., Buschmann M.D., (2004a) Positive Electric Potentials Detected at the Cartilage/Bath Interface During Compression and their Importance in Clinical Cartilage Diagnostics. Transactions of the 50th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, USA, 29:528. Poster
Quenneville E, Garon M, and Buschmann MD. (2004b) Convection of electrolyte through a charged membrane produces net charge at membrane interfaces. Polyelectrolytes 2004, #S2-23, Amherst, USA (2004) Poster
Quenneville, E., Binette, J. S., Garon, M., Legare, A., Meunier, M. and Buschmann, M. D. (2004c). Fabrication and characterization of nonplanar microelectrode array circuits for use in arthroscopic diagnosis of cartilage diseases. IEEE Trans Biomed Eng. 51(12): 2164-73. Abstract
2003
Garon M., Legare A., Quenneville E., Hurtig M., Buschmann M.D., (2003) Streaming Potential Based Arthroscopic Instrument Distinguishes Site-Specific Properties of Equine Articular Cartilage. Transactions of the 49th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 28:255.Slides | Abstract
Quenneville E., Garon M., Legare A., Hurtig M., Buschmann M.D., (2003a) Load and Streaming Potential Responses of Articular Cartilage as a Function of Compression Speed during Indentation. Transactions of the 49th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 28:659. Poster
Quenneville E, Garon M, Légaré A, Garon M, Buschmann MD. (2003b) New Arthroscopic Device for Functional Mapping of Articular Cartilage. Trans. Joint IXth Canadian Connective Tissue Conference, #SS-1, Montreal, Canada, July 2003.
2002
Buschmann MD, Légaré A, Quenneville E, Garon M, and Hurtig MB. (2002) Mapping of the Functional Properties of Articular Cartilage via Streaming Potentials Measured with a New Arthroscopic Device. Trans. Osteoarthritis Consensus Conference, Toronto, April 2002
Garon M., Legare A., Guardo R., Savard P., Buschmann, M.D. (2002) Streaming Potentials Maps are Spatially Resolved Indicators of Amplitude, Frequency and Ionic Strength Dependant Responses of Articular Cartilage to Load. Journal of Biomechanics. 35, pp.207-216. Abstract
Legare A., Garon M., Guardo R., Savard P., Buschmann, M.D. (2002) Detection and Analysis of Cartilage Degeneration by Spatially Resolved Streaming Potentials. Journal of Orthopaedic Research. 20(4), pp. 208-215. Abstract
Quenneville E, Garon M, Légaré A, Garon M, Hurtig M, Buschmann MD. (2002a) Diagnostic Mapping of Articular Cartilage with a New Arthroscopic Device. Trans. International Cartilage Repair Society, Toronto, June 2002. Poster
Quenneville E, Garon M, Légaré A, Garon M, Hurtig M, and Buschmann MD. (2002b) Diagnostic Mapping of Bovine and Equine Articular Cartilage with a New Arthroscopic Device. Trans. Canadian Arthritis Network, Calgary, September 2002 Slides
2001
Garon M, Guardo R, and Buschmann MD. (2001) Estimation and sensitivity to cartilage degradation of electromechanical coupling coefficients derived using spatially resolved streaming potentials. Trans. Orthopaedic Research Society. San Francisco, USA, February 2001. Poster
Légaré A, Garon M, Binette F and Buschmann MD. (2001) Evaluation of Cartilage Quality using Streaming Potential Maps. International Cartilage Repair Society, 2001. Poster
Quenneville E, Légaré A, Garon M, Buschmann MD. (2001) Evaluation of an Arthroscopic Probe for the diagnosis of Cartilage Degradation. Canadian Arthitis Network Conference, Calgary, September 2001. Poster
2000
Buschmann, MD. (2000) Spatial Resolution of Mechanical Phenomena in Loaded Cartilage. The Whitaker Foundation Conference, San Diego, August 2000.
Légaré A, Garon M, Binette F and Buschmann MD. (2000a) Evaluation of Cartilage Quality using Streaming Potential Maps. International Cartilage Repair Society, Sweden, April 2000. Poster
Légaré A. (2000b) Functionnal Evaluation of Joint Diseases and Repair through Arthroscopic Non-Destructive Streaming Potential Measurements. Emerging Medical Technologies, California, 2000
1999
Légaré A, Garon M, Binette F, Guardo R, Savard P, and Buschmann MD. (1999) Characterization of Connective Tissue Using Streaming Potential Maps. Transactions 5th Canadian Connective Tissue Conference. Montreal, Canada, June 1999. Slides
1998
Buschmann, M. D., Guardo, R., Garon, M., Savard, P. and Le Guyader, P. (1998). A medical device for the diagnosis of cartilage degeneration via spatial mapping of compression-induced electrical potentials. Patent 5779651 (United States).
Légaré, A. (1998a). Détection de la dégénérescence du cartilage articulaire par la distribution spatiale des potentiels d'écoulement (Detection of Articulare Cartilage Degeneration by Streaming Potentials Spatial Distribution), Biomedical Engineering Institute, Montreal, Ecole Polytechnique of Montreal. Master in Applied Science (M.A.Sc.) Thesis.
Legare A., Garon M., Guardo R., LeGuyader P., Savard P., Buschmann M.D. (1998b) Detection of Cartilage Degeneration by Spatially Resolved Streaming Potentials. Transactions of the 44th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 23:659. Slides
1997
Garon M., Guardo R., Savard P., Buschmann M.D. (1997) Spatially Resolved Detection of Streaming Potentials in Articular Cartilage. Transactions of the 43th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, USA, 22:80. Slides