系統(tǒng)簡介：
biomomentum廠家Mach-1軟組織壓縮、張力、剪切和扭矩測(cè)量分析系統(tǒng),Mach-1? Multiaxial Mechanical Testers是1999年推出的力學(xué)測(cè)試系統(tǒng)（圖1），*初用于測(cè)試軟骨，現(xiàn)在可以用于測(cè)試各種組織和軟材料的力學(xué)性質(zhì)。Mach-1體積小，采用模塊化設(shè)計(jì)且可以進(jìn)行定制，在生物材料研究中具有廣泛的應(yīng)用。
系統(tǒng)亮點(diǎn)：
l 大范圍高精度多軸測(cè)試：可測(cè)量動(dòng)態(tài)、靜態(tài)和各種波形的壓縮、張力、剪切和扭矩
l 可在標(biāo)準(zhǔn)的培養(yǎng)皿中進(jìn)行力學(xué)刺激實(shí)驗(yàn)
l 用戶友好的數(shù)據(jù)采集和分析軟件
l 可作為理想的教學(xué)工具
l 體積小，方便攜帶
l 可**測(cè)試微米至厘米范圍內(nèi)低力學(xué)性質(zhì)的樣品
Biomentum為提供多種標(biāo)準(zhǔn)和定制的附件來滿足不同的需要。Mach-1可更換壓縮桿對(duì)不同的細(xì)胞進(jìn)行測(cè)量，測(cè)試室和固定裝置也有很多種型號(hào)供客戶選擇。通過這些零件的組合，Mach-1可以對(duì)動(dòng)脈、關(guān)節(jié)軟骨、生物反應(yīng)器、骨、中央神經(jīng)系統(tǒng)、彈性纖維、胎膜、皮膚、水凝膠等材料實(shí)現(xiàn)表面力學(xué)譜測(cè)定（圖2 A）、壓痕實(shí)驗(yàn)（圖2 B）、非受限壓縮實(shí)驗(yàn)（圖2 C）、施加力學(xué)刺激（圖2 D）、肌腱張力測(cè)試（圖2 D）等功能。
Mechanical Testing System - Application Examples
Biomomentum offers a selection of standard and custom-designed accessories. Interchangeable compression rods can be provided with any Mach-1? system, each attached directly to the load cell for application-specific load measurements. A range of testing chambers and fixtures can also be designed and manufactured in adherence with the unique needs of the client. Examples of accessories offered by Biomomentum are depicted below with corresponding applications.
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Indentation on Articular Cartilage
Automated Indentation Mapping
Human (Sim et al., 2014)
Mice (Lavoie et al., 2014)
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Unconfined Compression
Chitosan Thermogel (Coutu et al., 2013)
Swine Growth Plate (Sergerie et al., 2009)
Agarose Gel (Tran-Khanh et al., 2005)
Cartilage Repair Scaffold (Hoemann et al., 2005)
Cartilage (Fortin et al., 2000)
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Mechanical Stimulation
Multi-Axial Mechanical Stimulation (Waldman et al., 2007)
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Tension Testing
Rabbit Patellar Tendon (Clemmer et al., 2010)
Wound Healing 
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Mechanical Testing System
The Mach-1? is a mechanical testing system commercially available since 1999. Originally developed for cartilage testing, this multiple-axis tester is now being used in various configurations for the evaluation of mechanical properties of tissues and soft material. Due to its small footprint, modular design and customization features, the Mach-1? offers versatility in numerous biological, biomaterial, and material testing applications.
iomomentum has developed innovative functionalities for Automated Indentation Mapping of articular cartilage samples with the use of the unique multiple-axis capabilities of the Mach-1? V500css.
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Mach-1? Models
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V500c
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1 Stage for Compression / Tension Testing
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V500cs
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1 Vertical Stage & 1 Horizontal Stage for Compression / Tension and Shear Testing
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V500ct
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1 Vertical Stage & 1 Rotation Stage for Compression / Tension and Torsion Testing
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V500cst
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1 Vertical, 1 Horizontal & 1 Rotation Stage for Compression / Tension, Shear and Torsion Testing
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V500css
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1 Vertical & 2 Horizontal Stages for Compression / Tension and Shear (along 2 Axes) Testing
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Pitney, M., van Niekerk, E., Dokos, S., Pelletier, M., & Walsh, W. R. (2013). Longitudinal Stent Deformation: Importance of Stent Type and Stent Apposition.
American Journal of Biomedical Engineering, 3(3), 63-69.
Full Text
Coutu, J.-M. (2012). Influence de l'agent de contraste sur les propriétés du thermogel de chitosane vers un nouvel agent embolisant pour les anévrismes. (Ma?trise), école de technologie supérieure. Abstract
Suen, R. S., Rampersad, S. N., Stewart, D. J., & Courtman, D. W. (2011). Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice. The American journal of pathology, 179(3), 1549-1559. Abstract
Arribas, S. M., Briones, A. M., Bellingham, C., González, M. C., Salaices, M., Liu, K., Wang, Y., Hinek, A. (2008). Heightened aberrant deposition of hard-wearing elastin in conduit arteries of prehypertensive SHR is associated with increased stiffness and inward remodeling. Am J Physiol Heart Circ Physiol, 295(6), H2299-2307. Abstract
Iliopoulos, J. (2006). The Aortic Wrap Procedure: A Surgical Method of Treating Age-Related Aortic Dilatation and Stiffness. (PhD), University of New South Wales, Sydney.
Mechanical Testing System - Scientific Publications & Material
Articular Cartilage
S. Sim, A. Chevrier, M. Garon, E. Quenneville and Michael D. Buschmann. Novel Technique to Map the Biomechanical Properties of Entire Articular Surfaces Using Indentation to Identify Early Osteoarthritis-like Regions. Podium presentation ID: 18-5. Annual conference of the European Society for Biomaterials, August 31 - September 3, 2014, Liverpool, UK. Presentation
S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann (2014) Indentation Method to Map Mechanical Properties of Articular Surface to Identify Degenerated Regions. Podium presentation ID: OP-Sat-3-4. Annual Meeting of the Biomedical Engineering Society, October 22-25, 2014, San Antonio, TX, USA. Presentation
J.-F. Lavoie, S. Sim, A. Moreau, C.-é. Aubin, E. Quenneville, M. Garon, and M.D. Bushmann (2014) Mapping Biomechanical Properties of Mice Articular Surfaces Using Indentation: Preliminary Results. Poster ID: P-Th-183.Poster
S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann (2014) Novel Technique to Map the Biomechanical Properties of Entire Articular Surfaces Using Indentation to Identify Degenerated (Osteoarthritis-like) Cartilage. Poster 2229. World Congress on Biomechanics, July 6-11, 2014, Boston, MA, USA. Poster
Mechanical Testing System - Scientific Publications & Material
S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann (2014) Novel Technique to Map the Biomechanical Properties of Entire Articular Surfaces Using Indentation to Identify Early Osteoarthritis-like Regions. Podium presentation ID:O7.05. International Conference on BioTribology, May 11-14, 2014, Toronto, Canada. Presentation
Qin, J., Chow, S. K.-H., Guo, A., Wong, W.-N., Leung, K.-S., & Cheung, W.-H. (2014) Low Magnitude High Frequency Vibration Accelerated Cartilage Degeneration but Improved Epiphyseal Bone Formation in Anterior Cruciate Ligament Transect Induced Osteoarthritis Rat Model. Osteoarthritis and Cartilage. Abstract
Sim, S., Lavoie, J. F., Moreau, A., Quenneville, E., Garon, M., & Buschmann, M. D. (2014) Novel Technique to Map the Biomechanical Properties of Entire Mice Articular Surfaces Using Indentation. Osteoarthritis and Cartilage, 22(1), 541. World Congress on Osteoarthritis, April 2014, Paris, France. Poster
S. Sim, A. Chevrier, M. Garon, E. Quenneville and M.D. Buschmann. Novel Technique to Map the Biomechanical Properties of Entire Articular Surfaces Using Indentation to Identify Osteoarthritis-like Regions. Paper presented at the Transactions of the 60th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 2015. Poster
Sim, S., Quenneville, E., Garon, M., Hoemann, C. D., Hurtig, M., & Buschmann, M. D. (2013) Evaluation of a novel technique to map the mechanical properties of an entire articular surface in indentation. Paper presented at the Transactions International Cartilage Repair Society, 11.2.9, Izmir, Turkey. Presentation
Chan, E. F., Liu, I.-L., Semler, E. J., Aberman, H. M., Simon, T. M., Chen, A. C., Truncale, K.G., Sah, R. L. (2012) Association of 3-dimensional cartilage and bone structure with articular cartilage properties in and adjacent to autologous osteochondral grafts after 6 and 12 months in a goat model. Cartilage, 3(3), 255-266. Abstract
Seifzadeh, A., Oguamanam, D., Trutiak, N., Hurtig, M., & Papini, M. (2012). Determination of nonlinear fibre-reinforced biphasic poroviscoelastic constitutive parameters of articular cartilage using stress relaxation indentation testing and an optimizing finite element analysis. Computer methods and programs in biomedicine, 107(2), 315-326. Abstract
Report following the ICRS Laboratory Skills Course in Translational Science in Montreal (Quebec, Canada), from May 31 to June 3, 2011. Report
Changoor, A., Garon, M., Hurtig, M., Buschmann, M., Quenneville, E., & Coutu, J. (2011). Streaming potential-based arthroscopic device is sensitive to cartilage changes immediately post-impact in an equine cartilage injury model.Journal of biomechanical engineering, 133(6), 061005. Abstract
Changoor, A., Yaroshinsky, A., Buschmann, M. D., & Fereydoonzad, L. (2010). Effects of refrigeration and freezing on the electromechanical and biomechanical properties of articular cartilage. Journal of biomechanical engineering, 132(6), 064502. Abstract
Hwang, J., Kyubwa, E. M., Bae, W. C., Bugbee, W. D., Masuda, K., & Sah, R. L. (2010). In Vitro Calcification of Immature Bovine Articular Cartilage Formation of a Functional Zone of Calcified Cartilage. Cartilage, 1(4), 287-297. doi: 10.1177/1947603510369552 Abstract
Lane, J., Healey, R., Chen, A., Sah, R., & Amiel, D. (2010). Can osteochondral grafting be augmented with microfracture in an extended-size lesion of articular cartilage? . Am J Sports Med. 2010 Jul, 38(7), 1316-1323. Abstract
Nguyen, Q. T., Wong, B. L., Chun, J., Yoon, Y. C., Talke, F. E., & Sah, R. L. (2010). Macroscopic assessment of cartilage shear: Effects of counter-surface roughness, synovial fluid lubricant, and compression offset. Journal of biomechanics, 43(9), 1787-1793. Abstract
Wong, B. L., Bae, W. C., Chun, J., Gratz, K. R., Lotz, M., & Sah, R. L. (2008). Biomechanics of cartilage articulation: effects of lubrication and degeneration on shear deformation. Arthritis & Rheumatism, 58(7), 2065-2074. Abstract
Bae, W., Schumacher, B., & Sah, R. (2007). Indentation probing of human articular cartilage: effect on chondrocyte viability. Osteoarthritis and Cartilage, 15(1), 9-18. Abstract
Horstman, C., McLaughlin, R., Elder, S., Pool, R., Read, R., & Boyle, C. (2006). Biomechanical and metabolic changes within rabbit articular cartilage following treatment with radiofrequency energy. Paper presented at the Podium presentation at the 2nd Annual World Veterinary Orthopaedic Congress, Keystone, CO, USA.
Kandel, R., Grynpas, M., Pilliar, R., Lee, J., Wang, J., Waldman, S., Zalzal, P., Hurtig, M. (2006). Repair of osteochondral defects with biphasic cartilage-calcium polyphosphate constructs in a sheep model. Biomaterials, 27(22), 4120-4131.Abstract
Nugent, G. E. (2006). Biomechanical regulation of articular cartilage metabolism of proteoglycan 4 and articular surface integrity. (PhD), University of California, San Diego, USA. Full text
Nugent, G. E., Aneloski, N. M., Schmidt, T. A., Schumacher, B. L., Voegtline, M. S., & Sah, R. L. (2006). Dynamic shear stimulation of bovine cartilage biosynthesis of proteoglycan 4. Arthritis & Rheumatism, 54(6), 1888-1896. Abstract
Valverde-Franco, G., Binette, J. S., Li, W., Wang, H., Chai, S., Laflamme, F., Tran-Khanh, N., Quenneville, E., Meijers, T., Poole, A. R., Mort, J. S., Buschmann, M. D. and Henderson, J. E. (2006) Defects in articular cartilage metabolism and early arthritis in fibroblast growth factor receptor 3 deficient mice. Human molecular genetics, 15(11), 1783-1792.Abstract
Binette, J.S., Laflamme, F., Li, W., Valverde-Franco, G., Tran-Khanh, N., Quenneville, E., Henderson, J.E., and Buschmann, M.D. (2005) Novel Biomechanical Indentation Test Demonstrates Joint Surface Weakening in Mice Lacking Fibroblast Growth Factor Receptor 3 (FGFR3). Paper presented at the 11th Canadian Connective Tissue Conference, Montreal, QC, Canada. Poster
Bae, W., Law, A., Amiel, D., & Sah, R. (2004). Sensitivity of indentation testing to step-off edges and interface integrity in cartilage repair. Ann Biomed Eng, 32(3), 360-369. Abstract
Charlebois, M., McKee, M. D., & Buschmann, M. D. (2004). Nonlinear Tensile Properties of Bovine Articular Cartilage and Their Variation With Age and Depth. Journal of biomechanical engineering, 26, 129-137. Abstract
Nugent, G.E., Law, A.W., Wong, E.G., Temple, M.M., Bae, W.C., Chen, A.C., Kawcak, C.E., Sah, R.L. (2004) Site- and exercise-related variation in structure and function of cartilage from equine distal metacarpal condyle. Osteoarthritis Cartilage, 12(10), 826-833. Abstract
Quenneville, E., Binette, J.-S., Garon, M., Légaré, A., Meunier, M., & Buschmann, M. D. (2004). Fabrication and characterization of nonplanar microelectrode array circuits for use in arthroscopic diagnosis of cartilage diseases.Biomedical Engineering, IEEE Transactions on, 51(12), 2164-2173. Abstract
Garon, M., Légaré, A., Quenneville, E., Hurtig, M., & Buschmann, M. (2003). Streaming potential based arthroscopic instrument distinguishes site-specific properties of equine articular cartilage. Paper presented to the Transactions of the 49th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 28:255. Slides | Abstract
Langelier, E., & Buschmann, M. D. (2003). Increasing strain and strain rate strengthen transient stiffness but weaken the response to subsequent compression for articular cartilage in unconfined compression. Journal of biomechanics, 36(6), 853-859. Abstract
Quenneville, E., Garon, M., Légaré, A., & Buschmann, M. (2003). Load and streaming potential responses of articular cartilage as a function of compression speed during indentation. Paper presented at the Proc. Orthopaedic Research Society Meeting. Abstract
Thibault, M., Poole, A., & Buschmann, M. D. (2002). Cyclic compression of cartilage/bone explants in vitro leads to physical weakening, mechanical breakdown of collagen and release of matrix fragments. Journal of orthopaedic research, 20(6), 1266-1274. Abstract
Fortin, M., Soulhat, J., Shirazi-Adl, A., Hunziker, E., & Buschmann, M. D. (2000). Unconfined Compression of Articular Cartilage : Nonlinear Behavior and Comparison with a Fibril-Reinforced Biphasic Model. Journal of biomechanical engineering, 122(2), 189-195. Abstract
Legare, A., Garon, M., Binette, F., & Buschmann, M. (2000). Evaluation of cartilage quality using streaming potential maps. Transact ICRS, 3, 89. Poster
Dumont, J., Ionescu, M., Reiner, A., Poole, A. R., Tran-Khanh, N., Hoemann, C. D., McKee, M.D., Buschmann, M. D. (1999). Mature full-thickness articular cartilage explants attached to bone are physiologically stable over long-term culture in serum-free media. Connective tissue research, 40(4), 259-272. Abstract
Quenneville, E., Garon, M., Légaré, A., & Buschmann, M. (1999). Positive electric potentials detected at the cartilage/bath interface during compression and their importance in clinical cartilage diagnostics. ASME J. Biomech. Eng, 121, 340-347. Poster
Soulhat, J., Buschmann, M. D., & Shirazi-Adl, A. (1999). A fibril-network-reinforced biphasic model of cartilage in unconfined compression. Journal of Biomechanical Engineering, Jun, 121(3), 340-347. Abstract
Bioreactor
Viens, M., Chauvette, G., & Langelier, E. (2011). A Roadmap for the Design of Bioreactors in Mechanobiological Research and Engineering of Load-Bearing Tissues. Journal of Medical Devices, 5(4), 041006. doi: 10.1115/1.4005319Abstract
Bone
Liang, L. D., Wagner, A., Steeds, J., Hurtig, M., & Gordon, K. (2013). Characterization of the effect of microfracture surgery and angle of incidence on the structural properties of femoral bone. Studies by Undergraduate Researchers at Guelph, 7(1), 56-61. Full text
Lovric, V., Chen, D., Yu, Y., Oliver, R. A., Genin, F., & Walsh, W. R. (2012). Effects of demineralized bone matrix on tendon-bone healing in an intra-articular rodent model. The American journal of sports medicine, 40(10), 2365-2374. Abstract
Henderson, J. E., Gao, C., & Harvey, E. J. (2011). Skeletal Phenotyping in Rodents: Tissue Isolation and ManipulationOsteoporosis Research (pp. 13-28). London: Springer. Abstract
Engbretson, A. C. (2010). Determining the modulus of intact bovine vertebral cancellous bone tissue: Development and validation of a protocol. (Master), Queen's University. Abstract
Valverde-Franco, G., Liu, H., Davidson, D., Chai, S., Valderrama-Carvajal, H., Goltzman, D., Ornitz, D. M. and Henderson, J. E. (2004) Defective Bone Mineralization and Osteopenia in Young Adult Fgfr3-/- Mice. Hum Mol Genet, 13(3), 271-284.Abstract
Gillies, R., Gan, J., O'Gorman, M., & Walsh, W. (2001). BM11: Using CT's to Measure Bone Remodeling Changes.Australasian Physical & Engineering Sciences in Medicine, 24(4), 271. Abstract
Central Nervous System
Begonia, M. G., Liao, J., Horstemeyer, M. F., & Williams, L. N. (2009). Strain Rate Dependence in the Structure Property Relationship of Porcine Brain. Paper presented at the ASME 2009 Summer Bioengineering Conference. Abstract
Solomon, J. H. (2008). A Biorobotic Study of the Rat Whisker System: ProQuest. Abstract
Elastic Fibres
Miao, M., Sitarz, E., Bellingham, C. M., Won, E., Muiznieks, L. D., & Keeley, F. W. (2013). Sequence and domain arrangements influence mechanical properties of elastin-like polymeric elastomers. Biopolymers, 99(6), 392-407.Abstract
He, D. (2012). The Sequence and Function Relationship of Elastin: How Repetitive Sequences can Influence the Physical Properties of Elastin. (Doctoral), University of Toronto. Abstract
He, D., Miao, M., Sitarz, E. E., Muiznieks, L. D., Reichheld, S., Stahl, R. J., Keeley, F. W., Parkinson, J. (2012). Polymorphisms in the Human Tropoelastin Gene Modify In Vitro Self-Assembly and Mechanical Properties of Elastin-Like Polypeptides. PloS one, 7(9), e46130. doi: 10.1371/journal.pone.0046130 Abstract
Vieth, S., Bellingham, C., Keeley, F., Hodge, S., & Rousseau, D. (2007). Microstructural and tensile properties of elastin-based polypeptides crosslinked with Genipin and pyrroloquinoline quinone. Biopolymers, 85(3), 199-206. Abstract
Fetal Membrane
Weed, B. C., Borazjani, A., Patnaik, S. S., Prabhu, R., Horstemeyer, M., Ryan, P. L., Franz, T., Williams, L.N., Liao, J. (2012). Stress State and Strain Rate Dependence of the Human Placenta. Annals of biomedical engineering, 40(10), 2255-2265. Abstract
Borazjani, A., Weed, B. C., Patnaik, S. S., Feugang, J. M., Christiansen, D., Elder, S. H., Ryan, P. L., Liao, J. (2011). A comparative biomechanical analysis of term fetal membranes in human and domestic species. American journal of obstetrics and gynecology, 204(4), 365. e325-365. e336. Abstract
Weed, B., Borazjani, A., Patnaik, S., Prabhu, R., Franz, T., Horstemeyer, M., Williams, L., Liao, J. (2011). Stress State Dependence of Human Placenta Mechanical Behavior. Paper presented at the ASME 2011 Summer Bioengineering Conference.
Growth Plate
Ménard, A.-L., Soulisse, C., Raymond, P., Londono, I., & Villemure, I. (2013). Effect of cold storage and freezing on the biomechanical properties of swine growth plate explants. Journal of biomechanical engineering. Abstract
Wosu, R., Sergerie, K., Lévesque, M., & Villemure, I. (2012). Mechanical properties of the porcine growth plate vary with developmental stage. Biomechanics and modeling in mechanobiology, 11(3-4), 303-312.
Sergerie, K., Parent, S., Beauchemin, P. F., Londo?o, I., Moldovan, F., & Villemure, I. (2011). Growth plate explants respond differently to in vitro static and dynamic loadings. Journal of orthopaedic research, 29(4), 473-480. Abstract
Valteau, B., Grimard, G., Londono, I., Moldovan, F., & Villemure, I. (2011). In vivo dynamic bone growth modulation is less detrimental but as effective as static growth modulation. Bone, 49(5), 996-1004. Abstract
Valteau, B. P. (2011). étude comparative in vivo de la compression statique et dynamique sur des vertèbres caudales de rat: effets sur le taux de croissance et sur l'histomorphométrie de la plaque de croissance. (Ma?trise), école Polytechnique de Montréal. Abstract
Sergerie, K., Gennaro, B., Eveno, A.-S., Dubois-Rioux, M.-C., Lacoursière, M.-O., & Villemure, I. (2009). Intrinsic Mechanical Properties of Porcine Growth Plates Vary With Developmental Stages. Paper presented at the Transactions of the 55th Annual Meeting of the Orthopaedic Research Society, Las Vegas, NV, USA
Sergerie, K., Lacoursière, M.-O., Lévesque, M., & Villemure, I. (2009). Mechanical Properties of the Porcine Growth Plate and its Three Zones From Unconfined Compression Tests. Journal of biomechanics, 42(4), 510-516. Abstract
Sergerie, K., Villemure, I., & Lacoursière, M.-O. (2008). Mechanical Properties of the Porcine Growth Plate and its Three Zones from Unconfined Compression Tests. Paper presented at the Transactions of the 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, USA.
Hair
Quist, B. W., Faruqi, R. A., & Hartmann, M. J. (2011). Variation in Young's modulus along the length of a rat vibrissa.Journal of biomechanics, 44(16), 2775-2781. Abstract
Birdwell, J. A., Solomon, J. H., Thajchayapong, M., Taylor, M. A., Cheely, M., Towal, R. B., Conradt, J., Hartmann, M. J. (2007). Biomechanical models for radial distance determination by the rat vibrissal system. Journal of neurophysiology, 98(4), 2439-2455. Abstract
Hand Soft Tissue
Wu, J. Z., Dong, R. G., Warren, C. M., Welcome, D. E., & McDowell, T. W. (2014). Analysis of the effects of surface stiffness on the contact interaction between a finger and a cylindrical handle using a three-dimensional hybrid model.Medical engineering & physics. Abstract
Wu, J. Z., Wimer, B. M., Welcome, D. E., & Dong, R. G. (2012). An analysis of contact stiffness between a finger and an object when wearing an air-cushioned glove: The effects of the air pressure. Medical engineering & physics, 34(3), 386-393. Abstract
Heart
Iliopoulos, J., Cornwall, G., Evans, R., Manganas, C., Thomas, K., Newman, D., & Walsh, W. (2004). Evaluation of a bioabsorable polylactide film in a large animal model for the reduction of retrosternal adhesions. Journal of Surgical Research, 118(2), 144-153. Abstract
Hydrogels
Coutu, J. M., Fatimi, A., Berrahmoune, S., Soulez, G., & Lerouge, S. (2013). A new radiopaque embolizing agent for the treatment of endoleaks after endovascular repair: Influence of contrast agent on chitosan thermogel properties. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 101(1), 153-161. Abstract
Machado Roque, A. I. (2013). Protein scaffolds for cell culture. (PhD), Newcastle University. Abstract
Owen, S. C., Fisher, S. A., Tam, R. Y., Nimmo, C. M., & Shoichet, M. S. (2013). Hyaluronic acid click hydrogels emulate the extracellular matrix. Langmuir, 29(24), 7393-7400. Abstract
Snyders, R., Shingel, K. I., Zabeida, O., Roberge, C., Faure, M. P., Martinu, L., & Klemberg-Sapieha, J. E. (2007). Mechanical and microstructural properties of hybrid poly (ethylene glycol)-soy protein hydrogels for wound dressing applications. Journal of Biomedical Materials Research Part A, 83(1), 88-97. Abstract
Gauthier, M., Luo, J., Calvet, D., Ni, C., Zhu, X., Garon, M., & Buschmann, M. (2004). Degree of crosslinking and mechanical properties of crosslinked poly (vinyl alcohol) beads for use in solid-phase organic synthesis. Polymer, 45(24), 8201-8210. Abstract
Jarry, C., Chaput, C., Chenite, A., Renaud, M. A., Buschmann, M., & Leroux, J. C. (2001). Effects of steam sterilization on thermogelling chitosan-based gels. Journal of biomedical materials research, 58(1), 127-135. Abstract
Intervertebral Discs
Recuerda, M., Périé, D., Gilbert, G., & Beaudoin, G. (2012). Assessment of mechanical properties of isolated bovine intervertebral discs from multi-parametric magnetic resonance imaging. BMC musculoskeletal disorders, 13(1), 195.Abstract
Recuerda, M. (2010). Caractérisation des propriétés mécaniques des disques intervertébraux et de leurs relations avec l imagerie quantitative par résonance magnétique. (Ma?trise), école Polytechnique de Montréal. Abstract
Lungs
Mammoto, A., Mammoto, T., Kanapathipillai, M., Yung, C. W., Jiang, E., Jiang, A., Lofgren, K., Gee, E. Ingber, D. E. (2013). Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics. Nature communications, 4, 1759. Abstract
Mammoto, T., Jiang, E., Jiang, A., & Mammoto, A. (2013). Extracellular Matrix Structure and Tissue Stiffness Control Postnatal Lung Development through the Lipoprotein Receptor-Related Protein 5/Tie2 Signaling System. American Journal of Respiratory Cell and Molecular Biology, 49(6), 1009-1018. Abstract
Hill, C. H., Ashwell, C. M., Nolin, S. J., Keeley, F., Billingham, C., Hinek, A., & Starcher, B. (2007). Dietary iron deficiency compromises normal development of elastic fibers in the aorta and lungs of chicks. The Journal of nutrition, 137(8), 1895-1900. Abstract
Pharmaceutical Tablets
Mulhbacher, J., Ispas-Szabo, P., Ouellet, M., Alex, S., & Mateescu, M. A. (2006). Mucoadhesive properties of cross-linked high amylose starch derivatives. International journal of biological macromolecules, 40(1), 9-14. Abstract
Ravenelle, F., Marchessault, R., Legare, A., & Buschmann, M. (2002). Mechanical properties and structure of swollen crosslinked high amylose starch tablets. Carbohydrate polymers, 47(3), 259-266. Abstract
Plantar Soft Tissue
Hayami, J. W., Waldman, S. D., & Amsden, B. G. (2013). Injectable, High Modulus, And Fatigue Resistant Composite Scaffold for Load-Bearing Soft Tissue Regeneration. Biomacromolecules, 14(12), 4236-4247. Abstract
Pai, S., Vawter, P. T., & Ledoux, W. R. (2013). The Effect of Prior Compression Tests on the Plantar Soft Tissue Compressive and Shear Properties. Journal of biomechanical engineering, 135(9), 094501.
Pai, S., & Ledoux, W. R. (2012). The shear mechanical properties of diabetic and non-diabetic plantar soft tissue.Journal of biomechanics, 45(2), 364-370. Summary, Abstract
Pai, S., Vawter, P., & Ledoux, W. (2012). The effect of prior compression tests on the plantar soft tissue compressive and shear elastic properties. Journal of Foot and Ankle Research 2012, 5(Suppl 1), 14. Abstract
Hayami, J. W., Waldman, S. D., & Amsden, B. G. (2011). A Photocurable Hydrogel/Elastomer Composite Scaffold with Bi-Continuous Morphology for Cell Encapsulation. Macromolecular bioscience, 11(12), 1672-1683. Abstract
Polymers
Surrao, D. C., Hayami, J. W., Waldman, S. D., & Amsden, B. G. (2010). Self-crimping, biodegradable, electrospun polymer microfibers. Biomacromolecules, 11(12), 3624-3629. Abstract
Zhu, X., Zhang, J., Gauthier, M., Luo, J., Meng, F., & Brisse, F. (2006). Large Uniform-Sized Polymer Beads for Use as Solid-Phase Supports Prepared by Ascension Polymerization. Journal of combinatorial chemistry, 8(1), 79-84. Abstract
Baradie, B., & Shoichet, M. S. (2005). Novel fluoro-terpolymers for coatings applications. Macromolecules, 38(13), 5560-5568. Full Text
Griesser, H. J., McLean, K. M., Kingshott, P., Beumer, G. J., Thissen, H., Muir, B. W., & Hamilton-Brown, P. (2001). BM9: Bioactive'Hybrid'Polymeric Biomaterials. Australasian Physical & Engineering Sciences in Medicine, 24(4), 270. Abstract
Force Sensors
Sundara-Rajan, K., Bestick, A., Rowe, G., Klute, G., Ledoux, W., Wang, H., & Mamishev, A. (2012). An interfacial stress sensor for biomechanical applications. Measurement Science and Technology, 23(8), 085701. Abstract
Sundara-Rajan, K., Rowe, G. I., Bestick, A., Mamishev, A. V., Klute, G. K., & Ledoux, W. R. (2010). Capacitive sensing of interfacial forces in prosthesis. Paper presented at the Medical Measurements and Applications Proceedings (MeMeA), 2010 IEEE International Workshop on. Abstract
Skin
Wood, J., Soldin, M., Shaw, T. J., & Szarko, M. (2014). The biomechanical and histological sequelae of common skin banking methods. Journal of biomechanics. Abstract
Bowser, J., Elder, S., Pasquali, M., Grady, J., Rashmir-Raven, A., Wills, R., & Swiderski, C. (2013). Tensile properties in collagen-rich tissues of Quarter Horses with hereditary equine regional dermal asthenia (HERDA). Equine veterinary journal. Abstract
Lu, X., Sundara-Rajan, K., Lu, W., & Mamishev, A. V. (2013). Transfer Function of Interfacial Stress Sensor for Artificial Skin Applications. Electron Devices, IEEE Transactions on, 60(8), 2640-2647. Abstract
Grady, J. G., Elder, S. H., Ryan, P. L., Swiderski, C. E., & Rashmir-Raven, A. M. (2009). Biomechanical and molecular characteristics of hereditary equine regional dermal asthenia in Quarter Horses. Veterinary dermatology, 20(5-6), 591-599. Abstract
Wu, J., Cutlip, R., Andrew, M., & Dong, R. (2007). Simultaneous determination of the nonlinear-elastic properties of skin and subcutaneous tissue in unconfined compression tests. Skin Res Technol, 13(1), 34-42. Abstract
Authier, S., Fournier, S., Chaurand, F., Gordon, C., Garon, M., Cloutier, L., & Troncy, E. (November 2006). Validation of a surgical wound healing model in Sprague-Dawley rats. Paper presented at the 27th Annual Meeting of the American College of Toxicology. Poster
Wu, J., Cutlip, R., Welcome, D., & Dong, R. (2006). Estimation of the viscous properties of skin and subcutaneous tissue in uniaxial stress relaxation tests. Biomed Mater Eng. 2006, 16(1), 53-66. Abstract
Wu, J., Dong, R., Smutz, W., & Schopper, A. (2003). Nonlinear and viscoelastic characteristics of skin under compression: experiment and analysis. Biomed Mater Eng, 13(4), 373-385. Abstract
Stem Cells
Leipzig, N. D., Wylie, R. G., Kim, H., & Shoichet, M. S. (2011). Differentiation of neural stem cells in three-dimensional growth factor-immobilized chitosan hydrogel scaffolds. Biomaterials, 32(1), 57-64. Abstract
Leipzig, N. D., Xu, C., Zahir, T., & Shoichet, M. S. (2010). Functional immobilization of interferon-gamma induces neuronal differentiation of neural stem cells. Journal of Biomedical Materials Research Part A, 93(2), 625-633. Abstract
Suture Materials
Vizesi, F., Jones, C., Lotz, N., Gianoutsos, M., & Walsh, W. R. (2008). Stress relaxation and creep: viscoelastic properties of common suture materials used for flexor tendon repair. The Journal of hand surgery, 33(2), 241-246. Abstract
Acton, D., Perry, A., Evans, R., Butler, A., Stephens, P., Bruce, W., Goldberg, J., Sonnabend, D., Walsh, W. (2004). The effect of two nonresorbable suture types on the mechanical performance over a metal suture anchor eyelet. Knee Surgery, Sports Traumatology, Arthroscopy, 12(2), 165-168. Abstract
Teeth
Jiménez Montenegro, V. C., Jones, A., Petocz, P., Gonzales, C., & Darendeliler, M. A. (2012). Physical properties of root cementum: Part 22. Root resorption after the application of light and heavy extrusive orthodontic forces: A microcomputed tomography study. American Journal of Orthodontics and Dentofacial Orthopedics, 141(1), e1-e9.Abstract
Phelan, A., Petocz, P., Walsh, W., Darendeliler, A., Soma, K. J., Thomson, W. M., Morgaine, K.C., Harding, W.J., Lim, E., Sameshima, G. (2012). The force-distance properties of attracting magnetic attachments for tooth movement in combination with clear sequential aligners. Australian orthodontic journal, 28(2), 159. Abstract
Tendons and Ligaments
Clemmer, J., Liao, J., Davis, D., Horstemeyer, M. F., & Williams, L. N. (2010). A mechanistic study for strain rate sensitivity of rabbit patellar tendon. Journal of biomechanics, 43(14), 2785-2791. Abstract
Scherman, P., Haddad, R., Scougall, P., & Walsh, W. R. (2010). Cross-sectional area and strength differences of fiberwire, prolene, and ticron sutures. The Journal of hand surgery, 35(5), 780-784. Abstract
Davis, D., Clemmer, J., Liao, J., Horsetemeyer, M. F., & Williams, L. N. (2009). Strain Rate Effects on Structure-Property Relationship in the Rabbit Patellar Tendon. Paper presented at the ASME 2009 Summer Bioengineering Conference.Abstract
Williams, L., Elder, S., Bouvard, J., & Horsetemeyer, M. (2008). The anisotropic compressive mechanical properties of the rabbit patellar tendon. Biorheology, 45(5), 577-586. Abstract
Schreuder, F., Scougall, P., Puchert, E., Vizesi, F., & Walsh, W. (2006). Effect of suture material on gap formation and failure in type 1 FDP avulsion repairs in a cadaver model. Clinical Biomechanics, 21(5), 481-484. Abstract
Latendresse, K., Dona, E., Scougall, P., Schreuder, F., Puchert, E., & Walsh, W. R. (2005). Cyclic testing of pullout sutures and micro-mitek suture anchors in flexor digitorum profundus tendon distal fixation. The Journal of hand surgery, 30(3), 471-478. Abstract
Matheson, G., Nicklin, S., Gianoutsous, M., & Walsh, W. (2005). Comparison of zone II flexor tendon repairs using an in vitro linear cyclic testing protocol. Clinical Biomechanics, 20(7), 718-722. Abstract
Butler, A. M., & Walsh, W. R. (2004). Mechanical response of ankle ligaments at low loads. Foot & ankle international, 25(1), 8-12. Abstract
Wu, J., Brumfield, A., Miller, G., Metheny, R., & Cutlip, R. (2004). Comparison of mechanical properties of rat tibialis anterior tendon evaluated using two different approaches. Biomed Mater Eng, 14(1), 13-22. Abstract
Diaz, R. Y., Gutierrez, V., Gonzalez, F. M., Dieguez, F. R., & Vergara, F. J. (2003). Paper# 84 Biologic dynamic patellar tendon repair. Arthroscopy: The Journal of Arthroscopic & Related Surgery, 19(6), 43. Abstract
Walsh, W., Svehla, M., & Gillies, R. (2002). Low Force Stress Relaxation of Ligament. Journal of Bone & Joint Surgery, British Volume, 84(SUPP III), 236-236. Abstract
Tissue Engineering - Annulus Fibrosus
Cho, H., Park, S. H., Park, K., Shim, J. W., Huang, J., Smith, R., Elder, S., Min, B. H., Hasty, K. A. (2013). Construction of a Tissue-Engineered Annulus Fibrosus. Artificial organs, 37(7), E131-E138. Abstract
Yeganegi, M. (2009). Characterization of a Biodegradable Electrospun Polyurethane Nanofiber Scaffold Suitable for Annulus Fibrosus Tissue Engineering. University of Toronto. Abstract
Kandel, R., & Santerre, J. P. (2008). Fibrous scaffold for use in soft tissue engineering. Google Patents. Full Text
Smith, L. J. (2008). Structure and Function of the Elastic Fibre Network of the Human Lumbar Anulus Fibrosus. (PhD), The University of Adelaide. Abstract
Smith, L. J., Byers, S., Costi, J. J., & Fazzalari, N. L. (2008). Elastic fibers enhance the mechanical integrity of the human lumbar anulus fibrosus in the radial direction. Annals of biomedical engineering, 36(2), 214-223. Abstract
Cho, H., Park, K., Shim, J., Elder, S., Huang, J., Min, B., Robertson, J.T., Hasty, K. (2007). Construction of a tissue-engineered annulus fibrosus. Paper presented at the Transactions of the 53rd Annual Meeting of the Orthopaedic Research Society, San Diego, CA, USA.
Smith, L. J., Byers, S., Costi, J. J., & Fazzalari, N. L. (2007). The Roles of Elastic Fibres and Glycosaminoglycans in the Radial Tensile Mechanics of the Human Lumbar Anulus Fibrosus. Paper presented at the ASME 2007 Summer Bioengineering Conference. Abstract
Tissue Engineering - Articular Cartilage
Brenner, J. M., Kunz, M., Tse, M. Y., Winterborn, A., Bardana, D. D., Pang, S. C., & Waldman, S. D. (2013). Development of large engineered cartilage constructs from a small population of cells. Biotechnology progress, 29(1), 213-221.Abstract
Mintz, B. R., & Cooper, J. A. (2013). Hybrid hyaluronic acid hydrogel/poly (?-caprolactone) scaffold provides mechanically favorable platform for cartilage tissue engineering studies. Journal of Biomedical Materials Research Part A Abstract
Petrera, M., Croos, D., Amritha, J., Iu, J., Hurtig, M., Kandel, R. A., & Theodoropoulos, J. S. (2013). Supplementation With Platelet-Rich Plasma Improves the In Vitro Formation of Tissue-Engineered Cartilage With Enhanced Mechanical Properties. Arthroscopy: The Journal of Arthroscopic & Related Surgery, 29(10), 1685-1692. Abstract
Brenner, J. (2012). Development and Validation of Large-Sized Engineering Cartilage Constructs in Full-Thickness Chondral Defects in a Rabbit Model. (Master), Queen's University. Abstract
Kaupp, J. A. (2012). Simulated Joint Loading Enhances the Expression of Superficial Zone Markers in Tissue Engineered Cartilage Constructs. (PhD), Queen's University. Abstract
Keeley, F., Rothstein, S., Rothstein, A., & Woodhouse, K. (2012). Synthetic peptide materials for joint reconstruction, repair and cushioning. Google Patents. Full Text
Khan, A. A. (2012). Effects of Additional Sodium Bicarbonate on Extra/intra Cellular Factors in a Continuous Flow Bioreactor for the Production of Tissue Engineered Articular Cartilage. (PhD), Queen's University. Abstract
Khan, A. A., & Surrao, D. C. (2011). The importance of bicarbonate and nonbicarbonate buffer systems in batch and continuous flow bioreactors for articular cartilage tissue engineering. Tissue Engineering Part C: Methods, 18(5), 358-368. Abstract
Lee, W. D., Hurtig, M. B., Kandel, R. A., & Stanford, W. L. (2011). Membrane culture of bone marrow stromal cells yields better tissue than pellet culture for engineering cartilage-bone substitute biphasic constructs in a two-step process.Tissue Engineering Part C: Methods, 17(9), 939-948. Abstract
Tran, S. C., Cooley, A. J., & Elder, S. H. (2011). Effect of a mechanical stimulation bioreactor on tissue engineered, scaffold-free cartilage. Biotechnology and bioengineering, 108(6), 1421-1429. Abstract
Croos, D., Amrith, J., Roughley, P. J., & Kandel, R. A. (2010). Improved bioengineered cartilage tissue formation following cyclic compression is dependent on upregulation of MT1-MMP. Journal of orthopaedic research, 28(7), 921-927. Abstract
Fan, J. C., & Waldman, S. D. (2010). The effect of intermittent static biaxial tensile strains on tissue engineered cartilage. Annals of biomedical engineering, 38(4), 1672-1682. Abstract
Hao, T., Wen, N., Cao, J.-K., Wang, H.-B., Lü, S.-H., Liu, T., Lin, Q-X., Duan, C-M.,Wang, C.-Y. (2010). The support of matrix accumulation and the promotion of sheep articular cartilage defects repair in vivo by chitosan hydrogels.Osteoarthritis and Cartilage, 18(2), 257-265. Abstract
Raizman, I., Croos, D., Amritha, J., Pilliar, R., & Kandel, R. A. (2010). Calcium regulates cyclic compression-induced early changes in chondrocytes during in vitro cartilage tissue formation. Cell calcium, 48(4), 232-242. Abstract
Spiteri, C., Raizman, I., Pilliar, R. M., & Kandel, R. A. (2010). Matrix accumulation by articular chondrocytes during mechanical stimulation is influenced by integrin-mediated cell spreading. Journal of Biomedical Materials Research Part A, 94(1), 122-129. Abstract
Usprech, J. (2010). A Therapeutic Dose of Adenosine Triphosphate (ATP) for Cartilage Tissue Engineering. (Master), Queen's University. Abstract
Waldman, S., Usprech, J., Flynn, L., & Khan, A. (2010). Harnessing the purinergic receptor pathway to develop functional engineered cartilage constructs. Osteoarthritis and Cartilage, 18(6), 864-872. Abstract
Dare, E. V., Griffith, M., Poitras, P., Kaupp, J. A., Waldman, S. D., Carlsson, D. J., Dervin, G., Mayoux, C., Hincke, M. T. (2009). Genipin cross-linked fibrin hydrogels for in vitro human articular cartilage tissue-engineered regeneration. Cells Tissues Organs, 190(6), 313-325. Abstract
De Croos, J., Pilliar, R., & Kandel, R. (2008). AP-1 DNA binding activity regulates the cartilage tissue remodeling process following cyclic compression in vitro. Biorheology, 45(3), 459-469. Abstract
De Croos, J., Jang, B., Dhaliwal, S., Grynpas, M., Pilliar, R., & Kandel, R. (2007). Membrane type-1 matrix metalloproteinase is induced following cyclic compression of in vitro grown bovine chondrocytes. Osteoarthritis and Cartilage, 15(11), 1301-1310. Abstract
Waldman, S. D., Couto, D. C., Grynpas, M. D., Pilliar, R. M., & Kandel, R. A. (2007). Multi-axial mechanical stimulation of tissue engineered cartilage: review. Eur Cell Mater, 13(613), 73-74. Abstract
Waldman, S., Couto, D., Grynpas, M., Pilliar, R., & Kandel, R. (2006). A single application of cyclic loading can accelerate matrix deposition and enhance the properties of tissue-engineered cartilage. Osteoarthritis and Cartilage, 14(4), 323-330. Abstract
De Croos, J., Dhaliwal, S., Grynpas, M., Pilliar, R., & Kandel, R. (2006). Cyclic compressive mechanical stimulation induces sequential catabolic and anabolic gene changes in chondrocytes resulting in increased extracellular matrix accumulation. Matrix Biology, 25(6), 323-331. Abstract
Hoemann, C., Sun, J., Legare, A., McKee, M., & Buschmann, M. (2005). Tissue engineering of cartilage using an injectable and adhesive chitosan-based cell-delivery vehicle. Osteoarthritis and Cartilage, 13(4), 318-329. Abstract
Tran-Khanh, N., Hoemann, C. D., McKee, M. D., Henderson, J. E., & Buschmann, M. D. (2005). Aged bovine chondrocytes display a diminished capacity to produce a collagen-rich, mechanically functional cartilage extracellular matrix. Journal of orthopaedic research, 23(6), 1354-1362. Poster, Abstract
Williams, G., Klein, T., & Sah, R. (2005). Cell density alters matrix accumulation in two distinct fractions and the mechanical integrity of alginate-chondrocyte constructs. Acta Biomater, 1(6), 625-633. Abstract
Waldman, S. D., Spiteri, C. G., Grynpas, M. D., Pilliar, R. M., & Kandel, R. A. (2004). Long-term intermittent compressive stimulation improves the composition and mechanical properties of tissue-engineered cartilage. Tissue engineering, 10(9-10), 1323-1331. Abstract
Waldman, S., Spiteri, C., Grynpas, M., Pilliar, R., & Kandel, R. (2003). Long-term intermittent shear deformation improves the quality of cartilaginous tissue formed in vitro. Journal of orthopaedic research, 21(4), 590-596. Abstract
Waldman, S. D., Grynpas, M. D., Pilliar, R. M., & Kandel, R. A. (2003). The use of specific chondrocyte populations to modulate the properties of tissue-engineered cartilage. Journal of orthopaedic research, 21(1), 132-138. Abstract
Waldman, S. D., Spiteri, C. G., Grynpas, M. D., Pilliar, R. M., Hong, J., & Kandel, R. A. (2003). Effect of biomechanical conditioning on cartilaginous tissue formation in vitro. The Journal of Bone & Joint Surgery, 85(suppl_2), 101-105.Abstract
Waldman, S. D., Grynpas, M. D., Pilliar, R. M., & Kandel, R. A. (2002). Characterization of cartilagenous tissue formed on calcium polyphosphate substrates in vitro. Journal of biomedical materials research, 62(3), 323-330. Abstract
Tissue Engineering - Auricle Cartilage
Giardini-Rosa, R., Joazeiro, P. P., Thomas, K., Collavino, K., Weber, J., & Waldman, S. D. (2014). Development of scaffold-free elastic cartilaginous constructs with structural similarities to auricular cartilage. Tissue Engineering Part A.Abstract
Tissue Engineering - Bone
Hollenstein, J., Terrier, A., Cory, E., Chen, A. C., Sah, R. L., & Pioletti, D. P. (2013). Mechanical evaluation of a tissue-engineered zone of calcification in a bone-hydrogel osteochondral construct. Computer methods in biomechanics and biomedical engineering(ahead-of-print), 1-6. doi: 10.1080/10255842.2013.794898 Abstract
Jarry, C., Shive, M., & Chenite, A. (2007). An injectable biomaterial for bone repair. Materials science forum, 539-543, 535-539. doi: 10.4028/www.scientific.net/MSF.539-543.535 Abstract
Tissue Engineering - Cardiac Tissue
Périé, D., Dahdah, N., Foudis, A., & Curnier, D. (2013). Multi-parametric MRI as an indirect evaluation tool of the mechanical properties of in-vitro cardiac tissues. BMC cardiovascular disorders, 13(1), 24-24. Abstract
Wang, B., Tedder, M. E., Perez, C. E., Wang, G., de Jongh Curry, A. L., To, F., Elder, S.H., Williams, L.N., Simionescu, D.T., Liao, J. (2012). Structural and biomechanical characterizations of porcine myocardial extracellular matrix. Journal of Materials Science: Materials in Medicine, 23(8), 1835-1847. Abstract
Tedder, M. E. B. (2010). Characterization and Evaluation of a Novel Tissue Engineered Aortic Heart Valve Construct.(PhD), Graduate School of Clemson University. Abstract
Wang, B., Borazjani, A., Tahai, M., de Jongh Curry, A. L., Simionescu, D. T., Guan, J., To, F., Elder, S.H., Liao, J. (2010). Fabrication of cardiac patch with decellularized porcine myocardial scaffold and bone marrow mononuclear cells.Journal of Biomedical Materials Research Part A, 94(4), 1100-1110. Abstract
Yip, C. Y. Y. (2010). Pathology of Calcific Aortic Valve Disease: The Role of Mechanical and Biochemical Stimuli in Modulating the Phenotype of and Calcification by Valvular Interstitial Cells. (PhD), University of Toronto. Full text
Yip, C., Chen, J., Zhao, R., & Simmons, C. (2009). Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix. Arterioscler Thromb Vasc Biol, 29(6), 936-942. Abstract
Plantenga, T. L. (2007). Design of a fixture and method for direct measurement of the shear modulus of thin, soft polyacrylamide substrates. Abstract
Liu, Z., Iliopoulos, J., Gillies, R., O'Rourke, M., Avolio, A., & Walsh, W. (2001). BM10: Cyclic Preconditioning of Sheep Aorta. Australasian Physical & Engineering Sciences in Medicine, 24(4), 271. Abstract
Tissue Engineering - Central Nervous System
Leipzig, N. D., & Shoichet, M. S. (2009). The effect of substrate stiffness on ***** neural stem cell behavior. Biomaterials, 30(36), 6867-6878. Abstract
Leipzig, N., & Shoichet, M. (2008). Neural stem cell 2D and 3D responses to substrate stiffness. Paper presented at the Biomedical Engineering Society Annual Fall Meeting, St. Louis, MO, USA.
Leipzig, N., & Shoichet, M. (2008). Photopolymerizable chitosan for studying the effects of substrate stiffness on neural stem cell differentiation. Paper presented at the World Biomaterials Congress 2008, Amsterdam, The Netherlands.
Leipzig, N., & Shoichet, M. (2007). Neural progenitor cell differentiation and the effects of substrate stiffness. Paper presented at the Stem Cell Network Annual General Meeting, Toronto, ON, Canada.
Tissue Engineering - Ligaments
Chen, F., Hayami, J. W., & Amsden, B. G. (2014). Electrospun Poly (L-lactide-co-acryloyl carbonate) Fibre Scaffolds With a Mechanically Stable Crimp Structure For Ligament Tissue Engineering. Biomacromolecules. Abstract
Surrao, D. (2012). Biomimetic scaffolds for ligament tissue engineering. (PhD), Queen's University. Abstract
Surrao, D. C., Fan, J. C., Waldman, S. D., & Amsden, B. G. (2012). A crimp-like microarchitecture improves tissue production in fibrous ligament scaffolds in response to mechanical stimuli. Acta biomaterialia, 8(10), 3704-3713.Abstract
Surrao, D. C., Waldman, S. D., & Amsden, B. G. (2012). Biomimetic poly (lactide) based fibrous scaffolds for ligament tissue engineering. Acta biomaterialia, 8(11), 3997-4006. Abstract
Hayami, J. W., Surrao, D. C., Waldman, S. D., & Amsden, B. G. (2010). Design and characterization of a biodegradable composite scaffold for ligament tissue engineering. Journal of Biomedical Materials Research Part A, 92(4), 1407-1420. Abstract
Wu, X., & Wang, X. (2010). Advanced bioreactor for ligament tissue engineering. Paper presented at the Mechatronics and Automation (ICMA), 2010 International Conference on. Abstract
Tissue Engineering - Nucleus Pulposus
Kandel, R. (2012). Intervertebral disc, Google Patents. Full text
Hamilton, D. J., Pilliar, R. M., Waldman, S., & Kandel, R. A. (2010). Effect of circumferential constraint on nucleus pulposus tissue in vitro. The Spine Journal, 10(2), 174-183. Abstract
Khan, O. F., Jean-Francois, J., & Sefton, M. V. (2010). MMP levels in the response to degradable implants in the presence of a hydroxamate-based matrix metalloproteinase sequestering biomaterial in vivo. Journal of Biomedical Materials Research Part A, 93(4), 1368-1379. Abstract
Séguin, C. A., Grynpas, M. D., Pilliar, R. M., Waldman, S. D., & Kandel, R. A. (2004). Tissue engineered nucleus pulposus tissue formed on a porous calcium polyphosphate substrate. Spine, 29(12), 1299-1306. Abstract